Spring 2018
(1-1:50PM)

   

TOPIC

 

Complete readings (using Nota Bene) BEFORE class
the complete Biofundamentals text is : HERE





 
           
Wednesday
17 January
    1. Introduction to the class - slides  

introduction to NB and beSocratic
Optional reading Mendel, Darwin & Evolution

           
Friday
19 January
   

2. Core ideas in molecular / cell biology
Reviewing important terms & concepts in molecular biology

 

Read: Ellis-van Creveld syndrome and the Amish
Complete introductory beSocratic survey
Review
Chapters 7-9 if necessary





 
Monday
22 January
   

3. Where do genes, alleles & mutations come from?

 

Read: Chapter 11 pp. 225-229
Read: Where do all those gene come from?

           
Wednesday
24 January
   

4. How do allelic differences / mutations influence gene function?

 

Read: Chapter 11 pp. 229-231

           
Friday
26 January
   

5. Reproduction in prokaryotes (conjugation)

 

Read: Chapter 12. pp. 232-234





 
Monday
29 January
   

6. Horizontal gene transfer
(transformation + transduction)

 

Read: Chapter 12. pp. 235-237
Read: Lateral gene transfer in eukaryotes: tip of the iceberg or of an ice cube?

           
Wednesday
31 January
   

7. Eukaryotic reproduction
- somatic (and checkpoints)

 

Read: Chapter 13. pp.238-241

           
Friday
2 February
   

8. (I will be away, no class)

 

 





 
Monday
5 February
   

9. Eukaryotic reproduction
- checkpoints

 

Read: Chapter 13. pp. 238-241

           
Wednesday
7 February
   

10.Eukaryotic reproduction -
Sex determination

 

Read: Chapter 13. pp. 241- 244

           
Friday
9 February
   

11.Eukaryotic reproduction -
Sex determination

 

Read: Chapter 13. pp. 241- 244





 
Monday
12 February
   

12.Eukaryotic reproduction (Meiosis)

 

Read: Chapter 13. pp. 244 - 248

           
Wednesday
14 February
   

13. Eukaryotic reproduction
(recombination)

 

Read: Chapter 13. pp. 244 - 248

           
Friday
16 February
   

14. Linkage and haplotypes

 

Read: Chapter 13. pp. 248 - 250


   
 
Monday
19 February
   

15. Imprinting

 

Read: Chapter 13. pp. 250- 251
Read Imprinting

           
Wednesday
21 February
   

16.X-inactivation

 

Read: Chapter 13. pp. 251- 252

           
Friday
13 February
   

17. review for midterm 1

 

 





 
Monday
26 February
   

18. Midterm EXAM 1

 

 

           
Wednesday
28 February
   

19. Discuss term paper / video
presentation topics

 

 

           
Friday
2 March
  `

10. Generating mutations + alleles I

 

Read: Chapter 14. pp.





 
Monday
5 March
   

21. Generating mutations + alleles II

 

Read: Chapter 14. pp.

           
Wednesday
7 March
   

22. Generating mutations + alleles I I

  Read: Chapter 14. pp.
           
Friday
9 March
   

23. Longer term evolution studies

 

Read: Chapter 14. pp.





 
Monday
12 March
   

24. Forward + reverse genetics I

 

Read: Chapter 14. pp.

           
Wednesday
14 March
   

25. Forward + reverse genetics I I

 

Read: Chapter 14. pp.

           
Friday
16 March
   

26. Getting Mendelian I

 

Read: Chapter 15. pp.





 
Monday
19 March
   

27. Alleles and Monohybrid cross

 

Read: Chapter 15. pp.

Wednesday
21 March
   

28. Chi square and significance I

 

Read: Chapter 15. pp.

           
Friday
23 March
   

29. Chi square and significance II

 

Read: Chapter 15. pp.





 
SPRING    
BREAK
 

 





 
Monday
2 April
   

30. Dihybrid crosses + linkage

 

Read: Chapter 15. pp.

           
Wednesday
4 April
   

31. Dihybrid crosses + interactions

 

Read: Chapter 15. pp.

           
Friday
6 April
   

32. mapping + synteny

 

Read: Chapter 15. pp.





 

Monday
9 April

   

33. midterm review

 

Complete beSocratic

           

Wednesday
11 April

   

34. midterm 2

 

 

           
Friday
13 April
   

35. Germ line alleles and human pathologies

 

Read: Chapter 16. pp.


   
 
Monday
16 April
   

36. Methods: Where are genes expressed

  Read: Chapter 16. pp.
           
Wednesday
18 April
   

37. Alleles (ExAC) and phenotypes

 

Read: Chapter 16. pp.

           
Friday
20 April
   

38. Genetic anticipation

 

Read: Chapter 16. pp.


   
 
Monday
23 April
   

39. GWAS, Ancestry & Forensics

 

Read: Chapter 16. pp. Listen to GWAS overview

           
Wednesday
25 April
   

40. Somatic mutations I

 

Read: Chapter 17. pp.

           
Friday
27 April
   

41. Somatic mutations II

 

Read: Chapter 17. pp.





 
Monday
30 April
   

42. Should biohanking be legal (even if it effects future generations)?

 

"I want to help humans genetically modify themselves" + "The FBI and biohackers: an unusual relationship"
Read: A history of the future

           

Wednesday
2 May

   

43.Course review

 

 

           
Friday
4 May
    Reading Day
   




 
To be announced
   
FINAL EXAM:
to be announced

In MCDB A120
 
dinosaurs
          16 December 2015 4:30 PM - 7:00 PM