Spring 2018
(1-1:50PM)

   

TOPIC (part 2 of biofundamentals her)
Last updated: 3 March 2018

 

Complete readings (using Nota Bene) BEFORE class
the complete Biofundamentals text is : HERE





 
           
Wednesday
17 January
    1. Introduction to the class - slides  

introduction to NB and beSocratic
Optional reading Mendel, Darwin & Evolution

           
Friday
19 January
   

2. Core ideas in molecular / cell biology
Reviewing important terms & concepts in molecular biology -
slides

 

Read: Ellis-van Creveld syndrome and the Amish
Complete
introductory beSocratic survey
Review
Chapters 7-9 if necessary





 
Monday
22 January
   

3. Where do genes, alleles & mutations come from? - slides

 

Read: Chapter 11 pp. 225-229
Read: Where do all those gene come from?

           
Wednesday
24 January
   

4. How do allelic differences / mutations influence gene function? - slides

 

Read: Chapter 11 pp. 229-231

           
Friday
26 January
   

5. finish molecular biology review - slides

 






 
Monday
29 January
   

6. Reproduction in prokaryotes (conjugation) - slides

 

Read: Chapter 12. pp. 232-234
optional: How afraid of human cloning should we be

           
Wednesday
31 January
   

7. Horizontal gene transfer
(transformation + transduction)
- slides

 

Read: Chapter 12. pp. 235-237
optional : Lateral gene transfer in eukaryotes: tip of the iceberg or of an ice cube?
optional: Researchers Discover 10 New Immune Systems in Bacteria

           
Friday
2 February
   

(I will be away, no class)

 

 





 
Monday
5 February
   

8. Eukaryotic reproduction
- somatic divisions & checkpoints - slides

 
Read: Chapter 13. pp. 238-241
optional: cell cycle regulation by checkpoints
           
Wednesday
7 February
   

9. Sex determination and meiosis introduced - slides

 

Read: Chapter 13. pp. 241- 244
Why Males Are Biology's Riskier Sex

           
Friday
9 February
   

10.Meiosis - slides

 

Read: Chapter 13. pp. 244- 248
The evolution of sex (a video lecture from Yale)





 
Monday
12 February
   

11.recombination slides

 

Read: Chapter 13. pp. 244 - 248

           
Wednesday
14 February
   

12. Linkage and haplotypes - slides

 

Read: Chapter 13. pp. 244 - 248

           
Friday
16 February
   

13. Imprinting slides

 

Read: Chapter 13. pp. 248 - 250
Read Imprinting


   
 
Monday
19 February
   

14.X-inactivation – slides

 

Read: Chapter 13. pp. 250- 252

           
Wednesday
21 February
   

15. in class practice exam

 

practice miderm

           
Friday
23 February
   

16. review for midterm 1

 

review questions you should be able to answer





 
Monday
26 February
   

17. Midterm EXAM 1

 

midterm exam answers

           
Wednesday
28 February
   

19. Discuss term paper / video
presentation topics

 

 

           
Friday
2 March
  `

20. Luria-Delbruck – slides

 

Read: Chapter 14. pp.253-256





 
Monday
5 March
   

21. Generating mutations – slides

 

Read: Chapter 14. pp.256-261 | READ CRISPR
optional: war in the womb (material-fetal conflict)

           
Wednesday
7 March
   

22. Making mutations Intelligently:
CRISPR and such - slides

 

Optional reading: The Ames Test and the Real World
READ review on CRISPR
Optional reading: a history of CRISPR-CAS

           
Friday
9 March
   

23. Getting Mendelian - slides

  Read: Chapter 15. pp.262-265




 
Monday
12 March
   

24. Chi square -slides

 

Read: Chapter 15. pp.265-269

           
Wednesday
14 March
   

25.Linkage - slides

 

Read: Chapter 15. pp. 269-271

           
Friday
16 March
   

26. linkage - slides

 

Read: Chapter 15. pp.271-274
optional reading: Gene Interactions & phenotype effects





 
Monday
19 March
   

27. genetic interactions - slides

 

Read: Chapter 15. pp. 274-276
Optional reading: Genetic modifiers and Oligogenic traits

           
Wednesday
21 March
   

28. interactions-evolution (Hardy-Weinberg)

 

Read: Chapter 15. pp.276-278

           
Friday
23 March
   

29. presenting first draft storyboards

 

course section two - topics to review





 
SPRING    
BREAK
 

 

 


 
Monday
2 April
   

30. practice midterm 2

 

practice midterm questions

           
Wednesday
4 April
   

31. midterm review

 

 

           
Friday
6 April
   

32. MIDTERM 2

 

answered midterm





 

Monday
9 April

   

33. Maternal effects and zygotic development - slides

 

Read: Chapter 16. 279-283

           

Wednesday
11 April

   

34. Germ line alleles and human pathologies - slides

 

Read: Chapter 16. pp. 279-283
Optional: Nothing in cancer makes sense except…

           
Friday
13 April
   

35. Mendelian and non-mendelian traits

 

Read: Chapter 16. pp. 283-287


   
 
Monday
16 April
   

36. Methods: Where are genes expressed

  Optional: Nothing in cancer makes sense except…
           
Wednesday
18 April
   

37. Methods completed

 

Read: Chapter 16. pp. 287-292

         
Sweet Tooth Gene Tied to Less Body Fat
Friday
20 April
   

38. First presentation for videos

 



   
 
Monday
23 April
   

39.complete first presentation for videos

 

 

           
Wednesday
25 April
   

40. GWAS

 

Read: Chapter 16. pp. 292-293
Listen to GWAS overview

           
Friday
27 April
   

41. Should biohacking be legal
(even if it effects future generations)?

 

READ: "I want to help humans genetically modify themselves"
+ Mail-Order CRISPR Kits
+ "The FBI and biohackers: an unusual relationship

optional reading for the curious:
A history of the future





 
Monday
30 April
   

42. course review - third section

 

practice miderm

           

Wednesday
2 May

   

43.complete Course review

 

optional reading for the curious: Royal Society Primer on Forensic DNA analysis

           
Friday
4 May
    Reading Day
  all videos due (film study) -optional .




 
To be announced
   
FINAL EXAM:
to be announced

In MCDB A120
 
dinosaurs
          16 December 2015 4:30 PM - 7:00 PM